Lexus LS460 unpleasant odor from A/C after one minute of use on Lexus LS460

Submitted by Vehicle Owner · Jun 23, 2025
Published by RepairPal

Problem overview

Some Lexus LS460 owners report experiencing unpleasant odors from the A/C after just one minute of use, which can be attributed to several potential issues. These owners often find that a clogged cabin air filter leads to musty smells when the A/C is activated, necessitating a check and possible replacement of the filter. Additionally, moisture accumulation in the A/C system can foster mold and mildew growth, resulting in foul odors that may require cleaning of the evaporator and ventilation system to resolve. Some owners also detect a chemical-like smell that could indicate a refrigerant leak, emphasizing the importance of having this issue inspected and repaired by a qualified mechanic. External contaminants, such as leaves or debris trapped in the HVAC system, can also contribute to unpleasant smells, which can often be remedied by removing any obstructions. Finally, bacterial growth within the A/C system may cause foul odors, prompting some owners to use antibacterial treatments designed for automotive A/C systems. If these solutions do not alleviate the issue, it is recommended to consult a professional mechanic or Lexus service center for a thorough inspection and diagnosis.

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